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Jeff Bezos Backs Neuroscience Startup Aiming to Crack the Brain's Core Algorithm

Jeff Bezos has invested $500 million in Flourish, a startup working to understand the brain's fundamental computational mechanisms. The company, now valued at $2.5 billion, is taking a neuroscience-first approach to AI development, studying how real biological neurons process information rather than relying solely on traditional machine learning architectures.

Unlike most AI companies that focus on scaling software models, Flourish aims to reverse-engineer what researchers call the brain's "core algorithm"—the fundamental way neurons encode, transmit, and process signals. This approach could potentially lead to more energy-efficient and adaptive AI systems, though the path from neuroscience insights to working AI systems remains challenging.

The substantial valuation reflects growing investor interest in alternative paths to advanced AI, particularly those that draw inspiration from biological systems. Critics note that while understanding the brain is valuable, translating those insights into practical AI systems has proven difficult in the past.

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