Edible Sea Squirts Yield Compound That May Counter Aging Effects in Mice
A team at Stanford University has identified a substance that appears to slow—or even reverse—several hallmarks of aging in animal tests. The compound, called plasmalogen, occurs naturally in edible sea squirts (a type of marine organism also known as Ciona intestinalis) and was fed to older mice over a study period.
The results were notable across multiple biological systems. Mice receiving plasmalogen supplements showed improvements in memory and learning tasks compared to control groups. Under the microscope, researchers observed that synapses—the connections between brain cells—appeared healthier and more robust. The treated animals also displayed reduced markers of inflammation, a factor strongly linked to age-related decline. Perhaps most visibly, several mice grew thicker, darker coats of fur during the study.
The scientists believe plasmalogens may work by encouraging the brain to regenerate and by protecting existing synapses from the deterioration that typically accompanies aging. While the findings are promising, researchers caution that results in mice do not directly translate to humans, and further studies will be needed to determine safety and efficacy in people.
The study adds to growing interest in nutraceuticals—food-derived compounds with potential medicinal effects—as a avenue for addressing age-related health challenges.